Publications by authors named "M Gilca"
Article Synopsis
- There is a lack of research on ethnomedical practices for children in Eastern Europe, especially in Romania, which has a strong tradition of using medicinal plants for treating childhood illnesses.
- A study involving 326 mothers in Southern Romania identified 25 different plants used for treating various ailments in children, with most knowledge passed down from family and healthcare providers.
- Findings revealed that education level influenced both the number of plants used and the range of illnesses treated, while residency (urban vs. rural) mainly affected how plants were sourced (harvested vs. purchased).
: Type 2 diabetes mellitus (T2DM) is a major cardiovascular risk factor. Nitric oxide (NO) is one of the many molecules that regulate vascular tone, and red blood cells (RBCs) are known to play an important role in adjusting cardiac function through NO export from RBCs. Our study prospectively investigated the L-arginine (L-arg)-nitric oxide (NO) metabolic pathway in the erythrocytes and plasma of subjects with T2DM.
View Article and Find Full Text PDFBitter Phytochemicals as Novel Candidates for Skin Disease Treatment.
Curr Issues Mol Biol
December 2023
Skin diseases represent a global healthcare challenge due to their rising incidence and substantial socio-economic burden. While biological, immunological, and targeted therapies have brought a revolution in improving quality of life and survival rates for certain dermatological conditions, there remains a stringent demand for new remedies. Nature has long served as an inspiration for drug development.
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- Targeting inflammation and its connection to cancer through taste receptors presents a novel treatment strategy, particularly focusing on how different tastes may influence cancer-related phytochemicals.* -
- The study analyzed 1527 phytochemicals and found that 461 exhibited anti-cancer activity; it highlighted a strong correlation between the anti-inflammatory and anti-cancer properties of these compounds.* -
- Results showed that bitter tastes were linked to a higher likelihood of anti-cancer activity, while sweet tastes correlated negatively, suggesting potential therapeutic uses for taste receptor modulating compounds.*
The taste of a herb influences its use in traditional medicine. A molecular basis for the taste-based patterns ruling the distribution of herbal (ethno) pharmacological activities may not be excluded. This study investigated the potential correlations between the anti-inflammatory activity (AIA) and the phytocompound taste and/or its chemical class.
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