Publications by authors named "M Gianni Perrucci"
Article Synopsis
- * Results indicated that participants were less likely to initiate volitional actions during the systole phase compared to diastole, suggesting that systole enhances inhibitory control over voluntary responses.
- * Further tests maintained the difference in voluntary action responses between systole and diastole, regardless of induced anxiety or increased heart rate, indicating that the heart's influence on decision-making operates independently of other physiological or psychological factors.
Objective: Cold atmospheric plasma (CAP) is a novel approach for cancer treatment. It can be used to treat liquids-plasma-activated media (PAM)-which are then transferred to the target as an exogenous source of reactive oxygen and nitrogen species (RONS). The present study aimed at chemically characterizing different PAM and assessing their in vitro selectivity against head and neck cancer cells (HNC).
View Article and Find Full Text PDFThis study addresses the widespread use of UV filters (UVFs) in cosmetic and solar products due to the negative effects of UV radiation, particularly in relation to melanoma risk. While these filters offer protection, their extensive application raises concerns about their environmental and health impacts. Organic UVFs, in particular, have been associated with endocrine disruption in aquatic species and coral reef damage.
View Article and Find Full Text PDFOvercoming treatment-resistant depression with machine-learning based tools: a study protocol combining EEG and clinical data to personalize glutamatergic and brain stimulation interventions (SelecTool Project).
Front Psychiatry
July 2024
Article Synopsis
- Treatment-Resistant Depression (TRD) is a significant health issue that's hard to tackle due to its complex nature and varied symptoms, prompting the need for better treatment strategies.
- The SelecTool Project is introduced as a computational tool that combines clinical data, EEG, and blood biomarkers using machine learning to personalize TRD treatments, specifically focusing on esketamine nasal spray and accelerated repetitive Transcranial Magnetic Stimulation.
- The project involves two main phases: first, a study with 100 TRD subjects to evaluate the effectiveness of treatments, and then training the tool to assist in managing an additional 20 subjects, ultimately aiming to improve TRD treatment outcomes through advanced data analysis.
Interoception, the ability to sense and interpret bodily sensations, has recently emerged as a crucial factor in substance use disorders, including smoking. However, the role of interoceptive awareness in tobacco use remains poorly understood. The relationship between interoceptive ability and addictive behavior is complex, and attempting to conceptualize it as a linear association is unlikely to fully capture the complexity of the mechanisms underlying cravings and urges.
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