Publications by authors named "M Giacomantonio"
Introduction: According to the theoretical model of Schema Therapy, each human being has basic needs that require natural satisfaction from childhood. When these emotional needs are frustrated, early maladaptive schemas (EMS) develop, leading to coping styles that are strategies to manage the pain caused by activated EMS. The study validates and standardizes the Schema Coping Inventory in the Italian population and evaluates correlations between psychological variables and the SCI.
View Article and Find Full Text PDFPrevious literature on conspiracy beliefs has an important gap, as it has almost completely excluded conspiracy beliefs relating to LGBTQ+ people. The purpose of the present research was to develop and validate a specific tool to measure the Gender Ideology and LGBTQ+ Lobby Conspiracies Beliefs: the GILC scale. Two independent data collections (N = 1.
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- - CD8 T cells are crucial for fighting viruses, and type I interferons quickly activate them after viral exposure, leading to changes in their behavior.
- - The study reveals that exposure to reovirus activates naïve CD8 T cells within 24 hours, highlighting a previously overlooked role of these cells in the immune response.
- - The activation of naïve CD8 T cells is dependent on a protein called STAT1 and is influenced by a metabolic process involving nicotinamide phosphoribosyl transferase (NAMPT), suggesting new insights into immune responses to viruses.
Expectations about the "Natural Order of Things" and Conspiracy Beliefs about COVID-19.
Int J Environ Res Public Health
August 2022
The COVID-19 pandemic represents an event that unsettled the social and economic life of many people. When individuals are faced with shocking events, they may need to find plausible explanations for such events to restore control and make sense of reality. The adoption of conspiracy beliefs may represent a functional strategy for this purpose.
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- - The study investigates how cancer cell energy metabolism, particularly NAD+ levels, influences the effectiveness of oncolytic viruses like reovirus in treating multiple myeloma.
- - Researchers found that lower NAD+ levels, from inhibiting the enzyme NAMPT, made multiple myeloma cells more susceptible to reovirus-induced killing, especially in cells with active p53 and a preference for mitochondrial metabolism.
- - The combination treatment of reovirus and NAD+ depletion led to significant mitochondrial dysfunction and cell death in specific myeloma cells, indicating that targeting NAD+ levels could enhance oncolytic virus therapies in multiple myeloma patients.