Publications by authors named "M Gerardin"

The bidirectional scattering-surface reflectance distribution function (BSSRDF) is a fundamental scattering quantity that characterizes the appearance of translucent materials. The few existing BSSRDF measurement facilities that ensure traceable results have shown the high complexity of such measurement, while only accounting for light scattered in the reflection hemisphere. We have developed an imaging device for measuring both the reflective and the transmissive part of the spectral BSSRDF.

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Background: In many countries, nitrous oxide is used in a gas mixture (EMONO) for short-term analgesia. Cases of addiction, with significant misuse, have been reported in hospitalized patients. Patients suffering from sickle cell disease (SCD) could represent a high-risk population for substance use disorder (SUD) due to their significant pain crisis and repeated use of EMONO.

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Article Synopsis
  • A study on the pharmacokinetics of lumacaftor/ivacaftor in children with cystic fibrosis (CF) highlights the importance of optimizing treatment based on individual differences.
  • Factors like body weight and liver function were found to significantly affect drug levels in patients, showing that each child may process the medication differently.
  • The research suggests that personalized dose adjustments and therapeutic drug monitoring could enhance treatment effectiveness in this vulnerable population.
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Background: Opioid-related mortality is a rising public health concern in France, where opioids were in 2021 implicated in 75% of overdose deaths. Opioid substitution treatment (OST) was implicated in almost half of deaths related to substance and drug abuse. Although naloxone could prevent 80% of these deaths, there are a number of barriers to the distribution of take-home naloxone (THN) among opioid users in France.

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By performing bidirectionnal reflectance distribution function (BRDF) measurements, we have identified backscattering as the main phenomenon involved in the appearance of dry nanocrystallized powders. We introduce an analytical and physically based BRDF model that relies on the enhanced backscattering theory to accurately reproduce BRDF measurements. These experimental data were performed on optically thick layers of dry powders with various grains' morphologies.

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