Publications by authors named "M Gelmi"
Article Synopsis
- Uveal melanoma (UM) primarily affects individuals with fair skin and light eyes, and researchers aimed to see if specific genetic variations (SNPs) related to eye color could predict patient outcomes.
- The study involved analyzing DNA from 392 UM patients to link their eye color genotypes with various tumor characteristics and survival rates.
- Results indicated that patients with the blue eye genotype (G/G of rs12913832) had worse survival rates and were more likely to have high-risk tumor features, suggesting a genetic factor in UM prognosis.
Article Synopsis
- The study aimed to better classify uveal melanoma (UM) cell lines by examining their genetic and expression profiles, particularly focusing on identifying any underlying genetic causes for their behavior.
- Researchers analyzed 14 UM cell lines using techniques like next-generation sequencing and SNP arrays to assess protein and mRNA expression, and to identify genetic variants.
- Results indicated that cell lines Mel285 and Mel290, which do not have typical UM mutations, possess distinct genetic alterations and expression profiles, making them potentially unsuitable for research on therapeutic targets for UM.
In June 2022, a gastroenteritis outbreak occurred in a town in Northern Italy, possibly associated with the ingestion of norovirus from public drinking water. Noroviruses are highly infectious RNA viruses, with high stability in the environment. They are the primary cause of non-bacterial gastroenteritis worldwide, and despite the fact that the disease is mainly self-limiting, norovirus infection can lead to severe illness in the immunocompromised, the elderly and children.
View Article and Find Full Text PDFSelf-assembled peptides are used for diverse applications in the biomedical and technological fields. The morphology and function of the assembled systems are dictated by the peptide sequence and length. In this work, a supramolecular catalyst was obtained upon self-assembly of the diphenylalanine peptide conjugated to a triphenylphosphine Au(I) complex in acetonitrile.
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