[Individualizing education for patients with diabetes attending an acute care unit].

Background: An increasing number of diagnostic procedures and shortened length of stay impede education for patients with diabetes mellitus attending an acute care unit. Therefore, an individualized approach to patient education may be more suitable.

Patients And Methods: The educational needs of inpatients with diabetes attending a department of general internal medicine were analyzed using a structured 5- to 10-minute interview.

Imipenem resistance in Acinetobacter baumanii is due to altered penicillin-binding proteins.

The comparison of a clinical Acinetobacter baumanii isolate (strain No. 4852/88) and its selected imipenem-resistant (IMR) clone exhibited a complex reorganization of the penicillin-binding proteins (PBPs) with diminished labelling of all PBPs except the 24-kD PBP which showed an increased binding of 14C-penicillin. This protein could not be saturated by preincubation of membranes with imipenem at 8-fold the MIC of imipenem, thus indicating PBP alterations responsible for imipenem resistance.