An institutional framework to support ethical fair and equitable artificial intelligence augmented care.

Coordinated access to multi-domain health data can facilitate the development and implementation of artificial intelligence-augmented clinical decision support (AI-CDS). However, scalable institutional frameworks supporting these activities are lacking. We present the PULSE framework, aimed to establish an integrative and ethically governed ecosystem for the patient-guided, patient-contextualized use of multi-domain health data for AI-augmented care.

Human Melanoma and Glioblastoma Cells Express Cathepsins Supporting Reovirus Moscow Strain Infection.

This study evaluates the oncolytic potential of the Moscow strain of reovirus against human metastatic melanoma and glioblastoma cells. The Moscow strain effectively infects and replicates within human melanoma cell lines and primary glioblastoma cells, while sparing non-malignant human cells. Infection leads to the selective destruction of neoplastic cells, mediated by functional viral replication.

Does sibling family structure matter in the emotion understanding development in preschoolers?

The objective of the study was to investigate the impact of sibling family structure -including the number of children, age gaps, presence of a twin, sibling position, and gender composition - on emotion understanding and its development in children aged 5-6 years. A total of 409 preschoolers participated. Emotion understanding was assessed using The Test of Emotion Comprehension at the baseline and then again at a 1-year follow-up.

Exploring the use of the perceived stress scale for children as an instrument for measuring stress among children and adolescents: a scoping review.

This review examines the application and findings related to the Perceived Stress Scale for Children (PSS-C) since its development by B. White in 2014. The PSS-C is designed to assess children's perceived stress, focusing on their subjective experience rather than objective stressors.