[Pharmaco-therapeutic evaluation of medical treatments of adult autistics and multi-handicapped patients in a public mental health unit].

Introduction: This paper presents a survey conducted on a population of multi-handicapped patients and autistic adults hospitalised long term in the Paul Guiraud mental health Hospital in Villejuif France.

Objective: The aim of the survey is to deepen the knowledge of the treatments for this specific population.

Methods: A preliminary medical investigation was conducted on the population in order to target different groups of patients.

[Nursing practices about preparation and administration of oral solutions in psychiatry].

Oral liquid drugs have many advantages in psychiatry (compliance, facility of administration) but they may be origin of medicinal iatrogenics (dose error). Since 2001, chemistry of Paul Guiraud's hospital (Villejuif) has developed recommendations about this galenic form and measured every two years practices evolution and respect of recommendations. In 2005, we analysed 601 prescriptions (100%) and collected 215 questionnaires (60% of answers).

[Changes in pharmacists practices (1996 - 2000) related to harm reduction policy (condoms, injecting equipment, methylmorphine) and maintenance therapy delivery (buprenorphine, methadone)].

Aims: To measure pharmacists involvement in harm reduction programs and in delivery of maintenance therapies in order to estimate their contribution to the new public health policy.

Method: A longitudinal study was conducted among 327 pharmacies located in the southern suburban area of Paris (28 communities) using a standardized questionnaire.

Results: The response rate was 95% in 1996 and 92% in 2000.

[Value of trimeprazine among hypnotics in a psychiatric facility].

Trimeprazine (TPZ) has been marketed in France since 1959, as tablets and solution containing respectively 5 mg and 40 mg/ml. TPZ is a phenothiazine derivative with known antihistaminic and sedative effects. The first approved indication for TPZ is in the treatment of allergy.