Publications by authors named "M Gattinara"
Article Synopsis
- Pyogenic granuloma (PG) is a benign growth on the skin or mucosa that appears as a painful red nodule and can lead to complications like bleeding and infections.
- Its exact cause is not well understood, but multiple lesions can arise from systemic conditions or certain medications, including cancer treatments and hormone therapies.
- A specific case involves a 21-year-old woman with juvenile systemic lupus erythematosus who developed multiple PGs during treatment with belimumab, suggesting that PG can be induced by rheumatologic medications.
The diagnosis of juvenile idiopathic arthritis (JIA) is often entrusted to the pediatric rheumatologist specialist. Timely referral to a specialized center is crucial. This study aims to assess the consultation and investigation patterns of patients with joint complaints before rheumatology referral.
View Article and Find Full Text PDFObjectives: This study aims to evaluate the efficacy and safety of JAK inhibitors (JAKi) in a monocentric cohort of adult patients with juvenile idiopathic arthritis (JIA).
Methods: Patients attending a rheumatology transition clinic were retrospectively included in case of: i) JIA diagnosis according to current classification criteria (1); ii) age ≥18 years and iii) treatment with JAKi for at least 3 months.
Results: Seventeen adult patients with JIA were treated with JAKi (as first JAKi, 9 patients (52.
Objectives: Limited information is available on the clinical features, treatment modalities and outcomes of the juvenile idiopathic arthritis (JIA) categories of enthesitis-related arthritis (ERA) and juvenile psoriatic arthritis (JPsA). This study was aimed to describe the characteristics of Italian children with ERA and JPsA and to compare them with those of patients with the other categories of JIA.
Methods: Patients were part of a multinational sample included in a study aimed to investigate the prevalence of disease categories, treatment approaches, and disease status in patients from across different geographical areas (EPOCA Study).
Article Synopsis
- Chronic recurrent multifocal osteomyelitis (CRMO) is a rare autoinflammatory disease primarily affecting children and adolescents, causing ongoing episodes of bone and joint inflammation, and may correlate with various skin conditions like psoriasis and acne.
- This paper focuses on a 16-year-old female patient diagnosed with CRMO who developed pyoderma gangrenosum (PG) lesions on her lower leg following treatment with the TNF-α inhibitor adalimumab.
- The study explores the potential link between PG and CRMO, suggesting PG might be a skin manifestation of CRMO, while also reviewing existing literature on drug-induced PG cases associated with TNF-α antagonists and discussing their common mechanisms.