Comparative Results of Treatment and Complications: Pedea in Open Ductus Arteriosus in Premature Infants.

The open ductus arteriosus (ODA) is the vessel through which the pathological communication between the aorta and the pulmonary artery persists after birth. Clinical manifestations depend on the size of the duct and the stage of hemodynamic disorders. The course of the defect varies from asymptomatic to extremely severe.

[ROLE OF FECAL VOLATILE ORGANIC COMPOUNDS IN THE DIAGNOSIS OF BRONCHOPULMONARY DYSPLASIA].

The aim of the study was to analyze fecal volatile organic compounds in premature babies born with a weight of less than 1,500 grams in order to identify predictors of BPD. The study presents the results of the study in parallel groups, which are represented by premature babies born with a weight of less than 1500 grams. In the course of scientific work, 137 children were examined, from which stool samples were taken on the 14th and 28th days of life to detect VOCs using gas chromatography with mass spectrometry (GC/MS).

[CLINICAL CASE OF SEVERE COMBINED IMMUNE DEFICIENCY].

In connection with the urgency of early diagnosis of severe combined immune deficiency, the case from the clinical practice of the National Science Center for Maternity and Childhood, Astana, was considered. This clinical case indicates that it is difficult to verify the diagnosis of severe combined failure, as the child was hospitalized in city clinics with various infectious diseases before receiving the right treatment more than 10 times in 4 months of life. Also, this clinical example confirms that the most effective method of treating this disorder at the present stage is bone marrow transplantation.

Greater Real-Life Diagnostic Efficacy of Allergen Molecule-Based Diagnosis for Prescription of Immunotherapy in an Area with Multiple Pollen Exposure.

Background: Allergen molecule-based diagnosis has been suggested to facilitate the identification of disease-causing allergen sources and the prescription of allergen-specific immunotherapy (AIT). The aim of the current study was to compare allergen molecule-based IgE serology with allergen extract-based skin testing for the identification of the disease-causing allergen sources. The study was conducted in an area where patients are exposed to pollen from multiple sources (trees, grasses, and weeds) at the same time to compare the diagnostic efficiency of the 2 forms of diagnosis.