Publications by authors named "M Gasparini"
Introduction: In patients with chronic coronary syndromes (CCS), the benefit of percutaneous coronary intervention (PCI) added to optimal medical therapy (OMT) remains unclear. The indication to PCI may be driven either by angiographic evaluation or ischemia assessment, thus depicting different potential strategies which have not yet been thoroughly compared.
Methods: Randomized controlled trials (RCTs) comparing OMT versus PCI angio-guided or versus PCI non-invasive or invasive ischemia guided were identified and compared via network meta-analysis.
Article Synopsis
- The Italian Fund for Alzheimer's enabled a survey in 2020 to analyze cognitive disorder centers, focusing on their organization, administrative features, and professional profiles.
- A recent survey showed a rise in using a Minimum Core Test (MCT) for neuropsychological assessments in these centers from 45.7% in 2015 to 57.1% in 2022, with regional differences noted.
- The presence of psychologists and being a university-affiliated center significantly increased the likelihood of MCT use, indicating the need for improved diagnostic practices and addressing regional disparities.
Determining the probability of success of a clinical trial using a prior distribution on the treatment effect can significantly enhance decision-making by the sponsor. In a group sequential design, the probability of success calculated at the design stage can be updated to incorporate the information disclosed by the Data Monitoring Committee (DMC), usually consisting in a simple statement that advises to continue or to stop the trial, either for efficacy or futility, following pre-specified rules defined in the protocol. We define the "probability of success post interim" as the probability of success conditioned on the assumption that the DMC recommends continuing the trial after an interim analysis.
View Article and Find Full Text PDFOur study aimed to determine the development of antibiotic resistance during the peri-pandemic period in a regional secondary care hospital using an interrupted time series analysis. . We analyzed data from seven years, accounting for 441,149 patient days.
View Article and Find Full Text PDFBackground: Sarcopenia is a muscle disease characterized by reduction of muscle strength and muscle mass. In RA, 25.9 to 43.
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