Publications by authors named "M Gasana"

Article Synopsis
  • - Rift Valley fever (RVF) was first confirmed in Rwanda's livestock in 2012, with significant outbreaks occurring in 2018 and 2022, showcasing its ongoing presence in the region.
  • - Genetic analysis of virus samples from these outbreaks revealed that a single lineage, C, was responsible, with connections to previous outbreaks in Uganda and East Africa.
  • - Detection of the RVFV Clone 13 vaccine strain in slaughterhouse animals suggests an occupational risk for workers in the meat industry, highlighting the need for a collaborative One Health approach to manage RVF outbreaks.
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The widespread misuse of antibiotics to combat bacterial infections in dairy farming is a global concern contributing to antimicrobial resistance (AMR). To gain insights within small-scale dairy farming, a study was conducted in Nyabihu district of Rwanda from September 2021 to April 2023 to assess practices and factors associated with antibiotic use, investigate antibiotic residues in cow milk and undertake a comprehensive training program to improve quality milk production. A mixed-methods approach, combining cross-sectional and longitudinal intervention studies, involved 42 regular dairy farmers from both open and zero-grazing systems delivering milk to the Union pour la Promotion des Cooperatives des Eleveurs en Nyabihu (UPROCENYA) milk collection center (MCC).

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  • - Life expectancy for people with HIV is improving, but the prevalence of non-communicable diseases, especially mental health disorders, is increasing, prompting a study in Rwanda to assess this issue.
  • - The study involved 428 participants from 12 HIV clinics, revealing that 16.4% had mental health disorders, with major depression being the most common; however, most were unaware or not receiving treatment.
  • - Mental health issues were tied to experiences of stigma and discrimination related to HIV, suggesting the need for better integration of mental health care in HIV services, potentially using trained HIV nurses for diagnosis.
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Article Synopsis
  • Multidrug-resistant tuberculosis (MDR-TB), identified by rifampicin resistance (RR), poses significant challenges in managing TB in Rwanda, requiring investigation into its transmission dynamics over 27 years.
  • The study involved analyzing the whole genome sequences of RR-TB isolates from three periods: before MDR-TB program management (1991-2005), during early program management (2006-2013), and during a more consolidated phase (2014-2018) when rifampicin drug-susceptibility testing was expanded.
  • The results identified 13 transmission clusters among RR-TB isolates, with a dominant clone named "Rwanda Rifampicin-Resistant clone" (R3clone) being responsible for 69.
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Background: African Trypanosomiases threaten the life of both humans and animals. Trypanosomes are transmitted by tsetse and other biting flies. In Rwanda, the African Animal Trypanosomiasis (AAT) endemic area is mainly around the tsetse-infested Akagera National Park (NP).

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