Publications by authors named "M Garigliany"
ZnO and TiO nanoparticles (NPs) are widely employed for their antibacterial properties, but their potential environmental impact is raising concerns. This study aimed to assess their single and combined effects at environmentally relevant concentrations (210 μg L) on rainbow trout (Oncorhynchus mykiss) gills microbiota and immune functions. 16S rRNA gene sequencing performed after 5 and 28 days of exposure suggests that TiO NPs had a more immediate impact on bacterial diversity, while prolonged exposure to the mixture altered community composition.
View Article and Find Full Text PDFUnlabelled: Microbial lipopeptides are synthesized by nonribosomal peptide synthetases and are composed of a hydrophobic fatty acid chain and a hydrophilic peptide moiety. These structurally diverse amphiphilic molecules can interact with biological membranes and possess various biological activities, including antiviral properties. This study aimed to evaluate the cytotoxicity and antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) of 15 diverse lipopeptides to understand their structure-activity relationships.
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- Canine idiopathic pulmonary fibrosis (CIPF) is a serious lung disease primarily affecting elderly West Highland white terriers and is linked to respiratory failure, with unknown causes.
- * The study aimed to assess the expression of fibroblast activation protein (FAP) in lung biopsies from CIPF-infected dogs and evaluate its potential as a biomarker for fibrosis activity.
- * Results showed that while FAP levels were low in the blood of affected dogs, FAP expression was significantly higher in lung tissues with active fibrosis, suggesting its role in monitoring disease severity.
The lung is constantly exposed to airborne pathogens and particles that can cause alveolar damage. Hence, appropriate repair responses are essential for gas exchange and life. Here, we deciphered the spatiotemporal trajectory and function of an atypical population of macrophages after lung injury.
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- Ongoing global changes, such as land conversion for agriculture and urbanization, are increasing human-primate interactions, leading to higher zoonotic disease risks, especially in diverse primate regions like Asia.
- A systematic review was conducted to identify and document zoonotic pathogens found in wild Asian primates, analyzing variations in pathogen types across different habitats (urban, rural, forest).
- The review uncovered 183 pathogens across 39 primate species but highlighted a lack of comprehensive studies and biases in research, emphasizing the need for a multidisciplinary One Health approach to enhance pathogen surveillance and mitigate human-primate disease transmission.