Increased default mode network activation in depression and social anxiety during upward social comparison.

Social comparisons are a core feature of human life. Theories posit that social comparisons play a critical role in depression and social anxiety triggering negative evaluations about the self, as well as negative emotions. We investigated the neural basis of social comparisons in participants with depression and/or social anxiety (MD-SA, n=56) and healthy controls (n=47) using functional magnetic resonance imaging (fMRI).

Simulated and experimental phantom data for multi-center quality assurance of quantitative susceptibility maps at 3 T, 7 T and 9.4 T.

Purpose: To develop methods for quality assurance of quantitative susceptibility mapping (QSM) using MRI at different magnetic field strengths, and scanners, using different MR-sequence protocols, and post-processing pipelines.

Methods: We built a custom phantom based on iron in two forms: homogeneous susceptibility ('free iron') and with fine-scaled variations in susceptibility ('clustered iron') at different iron concentrations. The phantom was measured at 3.

Automated prostate multi-regional segmentation in magnetic resonance using fully convolutional neural networks.

Objective: Automatic MR imaging segmentation of the prostate provides relevant clinical benefits for prostate cancer evaluation such as calculation of automated PSA density and other critical imaging biomarkers. Further, automated T2-weighted image segmentation of central-transition zone (CZ-TZ), peripheral zone (PZ), and seminal vesicle (SV) can help to evaluate clinically significant cancer following the PI-RADS v2.1 guidelines.

Intraindividual comparison of Ga-DOTATATE PET / CT vs C-Choline PET / CT in patients with prostate cancer in biochemical relapse: in vivo evaluation of the expression of somatostatin receptors.

Background And Objectives: To prospectively compare the detection rate of Ga-DOTATATE versus C-choline PET/CT in patients with prostate cancer in biochemical relapse, and to evaluate somatostatin receptor expression in vivo to plan targeted therapies (Lu-DOTATATE).

Material And Methods: We prospectively analysed 64 patients with biochemical relapse (median PSA: 4.25 ng/mL).

Ga-PSMA and C-Choline comparison using a tri-modality PET/CT-MRI (3.0 T) system with a dedicated shuttle.

Background: The aim of this study was to prospectively compare the detection rate of Ga-PSMA versus C-Choline in men with prostate cancer with biochemical recurrence and to demonstrate the added value of a tri-modality PET/CT-MRI system.

Methods: We analysed 36 patients who underwent both C-Choline PET/CT and Ga-PSMA PET/CT scanning within a time window of 1-2 weeks. Additionally, for the Ga-PSMA scan, we used a PET/CT-MRI (3.