Surgical treatment of persistent hyperinsulinemic hypoglycemia (PHH) (insulinoma and nesidioblastosis).

Background: The persistent hyperinsulinemic hypoglycemia is characterized by clinical symptoms that occur when the blood glucose levels drop below the normal range. Two pathological situations cause this clinical problem: The presence of a tumor of the pancreas secreting excessive amounts of insulin, known as insulinoma, and congenital beta-cell hyperplasia in the pancreas in children and noninsulinoma pancreatogenic hypoglycemia syndrome in adults.

Patients And Methods: Clinical characteristic and surgical outcome of a group of 20 patients operated on for this hypoglycemic syndrome; 18 for insulinoma and two for nesidioblastosis in children was studied.

[Necrotizing infections of the soft tissues].

Object: In necrotizing soft tissue infections (NSTI) may be implicated skin, subcutaneous tissue, fascia and skeletal muscle, and include different clinical entities associated with high morbidity and mortality rates. Diagnosis must be early and its initial management must be common.

Methods: A retrospective study of 24 patients diagnosed of NSTI is made.