Publications by authors named "M Ganner"
Article Synopsis
- * Lineage M1 has emerged as the primary cause of these invasive infections, showing reduced genetic diversity and fewer mutations compared to earlier M1 strains that date back to 2008.
- * Despite being undetected before, M1 clades rapidly spread across the UK after the COVID-19 pandemic, suggesting that waning immunity and specific genetic traits enhance their ability to cause epidemics and survive population bottlenecks.
Objective: Increased incidence of neonatal Staphylococcus capitis bacteraemia in summer 2020, London, raised suspicion of widespread multidrug-resistant clone NRCS-A. We set out to investigate the molecular epidemiology of this clone in neonatal units (NNUs) across the UK.
Methods: We conducted whole-genome sequencing (WGS) on presumptive S.
Article Synopsis
- Panton-Valentine leucocidin (PVL) toxin's role in infection severity is uncertain, leading to a study comparing outcomes in patients with PVL-positive and PVL-negative community-acquired (CA) bacteraemia.
- Data from August 2018 to August 2021 showed no significant link between PVL positivity and mortality or length of stay, with an odds ratio of 0.90 for mortality risk.
- However, PVL-positive patients had a lower likelihood of being readmitted within 90 days, indicating that PVL detection didn't correlate with worse outcomes in CA bacteraemia.
Background: Ethical and legal issues are increasingly being reported by health caregivers; however, little is known about the nature of these issues in geriatric care. These issues can improve work and care conditions in healthcare, and consequently, the health and welfare of older people.
Aim: This literature review aims to identify research focusing on ethical and legal issues in geriatric care, in order to give nurses and other health care workers an overview of existing grievances and possible solutions to take care of old patients in a both ethical and legally correct way.
Background: Vancomycin is frequently used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia; reduced susceptibility to vancomycin is therefore disturbing.
Methods: molecular epidemiological analysis of 81 MRSA bacteraemia isolates collected during 2002-10 in the province of Bolzano, northern Italy was performed. MICs of a range of antimicrobials were determined by agar microdilution, screening for hGISA was by Macro-Etest and Etest GRD and confirmed by PAP-AUC with vancomycin and teicoplanin.