Publications by authors named "M Gamo"

Article Synopsis
  • MPOX (monkeypox) is primarily found in Central and West Africa, but it started spreading in non-endemic countries in May 2022, indicating community transmission.
  • A study in Madrid involving 133 patients suspected of having MPOX found that 100 were confirmed cases, with a significant majority (71.0%) being HIV positive and primarily men with a mean age of 33.
  • The study highlighted specific clinical manifestations, such as higher instances of inguinal adenopathies and pustules, while noting no severe cases or significant differences between HIV-positive and HIV-negative patients regarding disease progression.
View Article and Find Full Text PDF

Plant biotechnology is rife with new advances in transformation and genome engineering techniques. A common requirement for delivery and coordinated expression in plant cells, however, places the design and assembly of transformation constructs at a crucial juncture as desired reagent suites grow more complex. Modular cloning principles have simplified some aspects of vector design, yet many important components remain unavailable or poorly adapted for rapid implementation in biotechnology research.

View Article and Find Full Text PDF
Article Synopsis
  • - This study investigated the incidence and variability of excessive cuff pressure in double-lumen tubes used during one-lung ventilation in lung surgeries, finding high rates of elevated pressure.
  • - The study analyzed data from 147 patients, revealing that 54.5% experienced increased cuff pressure, with various factors like age and sex influencing these elevations.
  • - Results showed a significant number of patients had excess cuff pressure for over 50% of the time, with poor correlation between durations of tracheal and bronchial cuff pressure increases.
View Article and Find Full Text PDF

The high-throughput molecular analysis of gene targeting (GT) events is made technically challenging by the residual presetabce of donor molecules. Large donor molecules restrict primer placement, resulting in long amplicons that cannot be readily analyzed using standard NGS pipelines or qPCR-based approaches such as ddPCR. In plants, removal of excess donor is time and resource intensive, often requiring plant regeneration and weeks to months of effort.

View Article and Find Full Text PDF