Publications by authors named "M Gadre"

Article Synopsis
  • Three-dimensional bioprinting is a promising technology for tissue engineering and regenerative medicine, using decellularized extracellular matrix (dECM) as a key material.
  • The decellularization process removes cellular components while preserving the ECM, which is crucial for providing structural and biochemical support for tissue regeneration.
  • The review addresses various decellularization methods, their benefits and limitations, and the development of dECM-derived bioinks for creating tissue-specific products.
View Article and Find Full Text PDF
Article Synopsis
  • The review discusses the potential of using tissue engineering to create functional organs, specifically focusing on repairing the liver to treat chronic disorders that currently rely on organ transplantation, which has significant drawbacks.
  • The liver is critical for many metabolic processes and chronic liver disease is a major global health issue, necessitating the development of in vitro models that accurately mimic the liver’s natural environment.
  • Three-dimensional bioprinting is highlighted as a promising technology in this field, allowing for precise cell distribution and the creation of complex structures, which could advance liver disease modeling and drug testing.
View Article and Find Full Text PDF

Background: The purpose of this study was to determine the impact of early exposure to play materials on motor development in high-risk infants.

Materials And Methods: A 1:1 parallel group randomised control study was conducted. A total of 36 participants were recruited, with 18 in each group.

View Article and Find Full Text PDF

Reducing the working temperature of solid oxide fuel cells is critical to their increased commercialization but is inhibited by the slow oxygen exchange kinetics at the cathode, which limits the overall rate of the oxygen reduction reaction. We use ab initio methods to develop a quantitative elementary reaction model of oxygen exchange in a representative cathode material, LaSrCoO, and predict that under operating conditions the rate-limiting step for oxygen incorporation from O gas on the stable, (001)-SrO surface is lateral (surface) diffusion of O-adatoms and oxygen surface vacancies. We predict that a high vacancy concentration on the metastable CoO termination enables a vacancy-assisted O dissociation that is 10-10 times faster than the rate limiting step on the Sr-rich (La,Sr)O termination.

View Article and Find Full Text PDF

In this work, we performed density functional theory (DFT) calculations with inclusion of Hubbard U corrections for the transition metal d-electrons, to investigate stability and electrocatalytic activities of the oxygen evolution reaction (OER) and oxygen reduction reaction (ORR) for the ABO3 (A = La; B = Cr, Mn, Fe, Co, and Ni) (001) surfaces. We showed surface binding energies of relevant ORR/OER species are coupled strongly to surface polarity and local oxidation states, giving large (∼1 eV scale per adsorbate) differences in binding between (001) AO and BO2 surfaces, where the more oxidized BO2 bare surfaces in general exhibit weak coverage dependence, while the more reduced AO bare surfaces of the LaCrO3, LaMnO3, and LaFeO3 perovskites with lower d-electron filling show strong/moderate coverage dependences. We then predicted that surface coverage can play a key role in determining surface stability, and when coverage effects are included the AO and BO2(001) surfaces have either similar stability or the AO surface is more stable, as found for 1 monolayer HO* covered AO surfaces of LaCrO3 and LaFeO3 under ORR conditions and 1 monolayer O* covered LaNiO3 AO surface under OER conditions.

View Article and Find Full Text PDF