Background: Long COVID remains a significant public health concern. This study investigated risk factors for long COVID in outpatient settings.
Methods: A US-based prospective survey study (clinicaltrials.
The global demand for blueberries has increased due to their health benefits, but postharvest losses, particularly firmness loss and decay, present significant challenges. This study evaluated the effects of high CO concentrations (15% and 20%) applied for 3 d at 1.0 °C on highbush (cv.
View Article and Find Full Text PDFEbola and Marburg (EBOV and MARV) filoviral infections lead to fatal hemorrhagic fevers and have caused over 30 outbreaks in the last 50 years. Currently, there are no FDA-approved small molecule therapeutics for effectively treating filoviral diseases. To address this unmet medical need, we have conducted a systematic structural optimization of an early lead compound, -(4-(4-methylpiperidin-1-yl)-3-(trifluoromethyl)phenyl)-4-(morpholinomethyl)benzamide (), borne from our previously reported hit-to-lead effort.
View Article and Find Full Text PDFUnderstanding shell morphology is central to taxonomic and evolutionary studies of bivalves. When traditional systematic studies find limitations in the recognition and classification of taxa, geometric morphometrics methods become a tool to tackle these uncertainties. Taxonomic difficulties are frequently found in systematics studies of the generally homoplastic Pitarinae (Venereidae).
View Article and Find Full Text PDFFew microorganisms are known to decarboxylate L-tryptophan, thereby producing tryptamine, a neuromodulator biogenic amine (BA) that can accumulate in cheese. Since lactic acid bacteria (LAB) are largely responsible for the production of other BA in this product, it was hypothesised that they would also be the main agents of tryptamine production. Using a rapid test based on the natural fluorescence of tryptamine, thousands of bacterial isolates from several cheese samples were screened.
View Article and Find Full Text PDF