Homocysteine is an independent predictor of long-term cardiac mortality in patients with stable coronary artery disease in the era of statins.

Background: Homocysteine (Hcy) is considered a risk factor for cardiovascular disease.

Objective: To explore the long-term prognostic value of Hcy in patients with stable coronary artery disease (CAD) in the era of statins.

Methods: A total of 876 consecutive patients with stable CAD were recruited and followed up for a median of 6.

High levels of lipoprotein (a) and premature acute coronary syndrome.

Background And Aims: High levels of lipoprotein(a) [Lp(a)] are associated with increased risk of acute coronary syndrome (ACS). We explored whether Lp(a) exhibits a stronger association with premature ACS.

Methods: A case-control study was conducted; 1457 patients with a history of ACS (54.

Short-term effects of Mediterranean-type diet intervention on soluble cellular adhesion molecules in subjects with abdominal obesity.

Background & Aims: Abdominal obesity (AO) is associated with increased risk for cardiovascular disease and with increased production of adhesion molecules. The present work examined the effect of a Mediterranean-style diet on soluble cellular adhesion molecules in individuals with AO.

Methods: Ninety subjects with AO without cardiovascular disease or diabetes mellitus were randomly allocated to the intervention or control group and were instructed to follow a Mediterranean-style diet for two months.

The impact of smoking on long-term outcome of patients with premature (≤35years) ST-segment elevation acute myocardial infarction.

Background: There are few data regarding the long-term prognosis of young survivors of acute myocardial infarction (AMI). We explored the long-term outcome in individuals who had sustained a premature ST-segment elevation AMI.

Methods: We recruited 257 consecutive patients who had survived their first AMI ≤35years of age.