Tribological Behavior and Mechanism of Silane-Bridged h-BN/MoS2 Hybrid Filling Epoxy Solid Lubricant Coatings.

To significantly improve the tribological performance of epoxy resin (EP), a novel h-BN/MoS composite was successfully synthesized using spherical MoS particles with lamellar self-assembly generated through the calcination method, followed by utilizing the "bridging effect" of a silane coupling agent to achieve a uniform and vertically oriented decoration of hexagonal boron nitride (h-BN) nanosheets on the MoS surface. The chemical composition and microstructure of the h-BN/MoS composite were systematically investigated. Furthermore, the enhancement effect of composites with various contents on the frictional properties of epoxy coatings was studied, and the mechanism was elucidated.

GSDMD-mediated mitochondrial dysfunction in marginal cells: A potential driver of inflammation and stria vascularis damage in CIHL.

Inflammation is among the known causes of cisplatin-induced hearing loss (CIHL), but its exact pathophysiological mechanisms remain unclear. Herein, we demonstrated that pyroptosis-a recently identified inflammatory type of regulated cell death dependent on gasdermin D (GSDMD)-was activated in the cochleae of cisplatin-treated mice, causing CIHL. Meanwhile, treatment with the GSDMD inhibitor necrosulfonamide alleviated CIHL in these mice.

Reliability and validity of the Chinese version of the stroke upper limb capacity scale.

Purpose: To evaluate the reliability and validity of the Chinese version of the Stroke Upper Limb Capacity Scale (SULCS) compared to the Wolf Motor Function Test (WMFT) and the Fugl-Meyer Assessment-Upper Extremity (FMA-UE).

Materials And Methods: Patients with hemiplegia after stroke ( = 60). The intraclass correlation coefficient (ICC) and corresponding 95% confidence intervals (CI) were used to explore the reliability, and Spearman's correlation coefficient was used to analyze validity.

Azilsartan Confers Protection Against Kainic Acid-Induced Hippocampal Neuron Damage by Upregulating Sirt3/Sod2 Pathway.

Epilepsy refers to a diverse group of neurological pathologies, coupled with a significant worldwide impact. Azilsartan, an angiotensin receptor blocker, is broadly applied as an antihypertensive medication. Considering that the neuroprotective potential of Azilsartan has been newly documented, our work was committed to characterizing the association of Azilsartan with epilepsy and its possible mechanism.

Analysis of Research Trends and Hot Spots on COPD Biomarkers from the Perspective of Bibliometrics.

Background: Background: Chronic obstructive pulmonary disease (COPD), a chronic respiratory condition with airflow limitation, is the fourth leading global cause of death. Biomarkers are key for classifying COPD, detecting exacerbations, guiding treatment, and prognosis. This article uses bibliometrics and visualization to analyze COPD biomarker research trends, providing insights for future studies.