Publications by authors named "M G Vashisht"

The aim of the current investigation is to explore the novel application of pumpkin, papaya, and orange peels as growth substrates for microalgae cultivation, with the overarching goal of advancing a sustainable "Agro to Agro" biorefinery paradigm. The research evaluates the integration of waste management practices into microalgal production, optimizing growth parameters to maximize output. Optimal concentrations of 2.

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Article Synopsis
  • Head and neck squamous cell carcinoma (HNSCC) is characterized by a high presence of tumor-infiltrating myeloid cells, but effective therapies targeting these cells are not available.
  • Researchers used a co-culture system to show that HNSCC cells boost the growth and maturation of tumor-associated myeloid cells, specifically tumor-associated macrophages (TAMs) and myeloid-derived suppressor cells (MDSCs).
  • By screening 70 kinase inhibitors, they identified specific drugs that can suppress different types of myeloid cells, with vatalanib, a VEGF-R inhibitor, showing promise in reducing tumor growth and myeloid cell populations in vivo.
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Human papilloma virus (HPV) is an etiological factor of head and neck squamous cell carcinoma (HNSCC). To investigate the role of HPV antigen in anti-tumor immunity, we established mouse models by expressing HPV16 E6 and E7 in a SCC tumor cell line. We obtained two HPV antigen-expressing clones (C-225 and C-100) transplantable into C57BL/6 recipients.

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Nitrogen (N) and phosphorus (P) are vital for crop growth. However, most agricultural systems have limited inherent ability to supply N and P to crops. Biochars (BCs) are strongly advocated in agrosystems and are known to improve the availability of N and P in crops through different chemical transformations.

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Deletion of TRAF2 or TRAF3 in B cells prolongs their survival. However, it remains unknown whether deletion of such factors affects B cells' ability to tolerate DNA damage, which can be induced by chemotherapeutics and cause apoptosis. Genetic alterations of TRAF2 or TRAF3 are observed in subsets of human B-cell lymphomas and B cell-specific deletion of TRAF3 led to lymphoma development in aged mice.

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