Publications by authors named "M G Strillacci"
Article Synopsis
- Italian local turkey populations are crucial for maintaining genetic diversity, and efforts should focus on in vivo preservation methods.
- Advanced genomic techniques, including whole genome sequencing and genotyping, revealed significant genetic variability and isolation among different turkey populations in Italy.
- Findings highlight the role of selective sweeps in shaping genetic traits related to heat stress and growth, suggesting potential benefits in adapting to climate change, which can inform conservation and selection strategies for these turkeys.
Genome-wide association studies (GWASs) are used to identify quantitative trait loci for phenotypic traits of interest. The use of multilocus mixed models allows to correct for population stratification and account for long-range linkage disequilibrium. In this study, GWASs were conducted to identify the genetic bases of milk production (milk yield, protein and fat composition, and yield) in two autochthonous dual-purpose cattle breeds from the Aosta Valley.
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- The domestication of turkeys dates back to 700-200 BC in Mexico, leading to the creation of various local turkey breeds through a collaborative effort.
- This research analyzes the mitochondrial DNA (mtDNA) of 73 turkeys from different populations, including Italian and American breeds, as well as wild turkeys from the USA and Mexico, to explore biodiversity and breed relationships.
- The study found 44 polymorphic sites and identified 32 unique haplotypes, with the most common ones (H1 and H2) showing different geographic distributions and highlighting greater mtDNA variability in USA and Mexican samples compared to others.
Article Synopsis
- Scrapie is a brain disease affecting sheep and goats, linked to the prion protein gene (PRNP), which determines animals' susceptibility to the disease.
- At a European level, disease surveillance is critical, with specific gene variations (K222, D/S146) identified as potential resistance factors for controlling scrapie.
- In a study of 956 goats in Italy's Lombardy region, researchers found genetic variations within the PRNP gene that could influence susceptibility to scrapie, discovering ten distinct haplotypes and highlighting the need for genetic management in disease prevention.
Article Synopsis
- Copy Number Variants (CNVs) are genetic modifications in DNA that can involve large duplications or deletions of base pairs, affecting traits and showing genetic diversity related to environmental adaptation.
- The study analyzed over 4,000 Holstein cows using the GGP bovine 100K SNP chip to detect CNVs, revealing 123,814 CNVs grouped into 1,397 CNV regions (CNVRs).
- The findings indicated variability among the cows and highlighted the potential of CNVs to enhance genomic predictions for traits like milk production and quality, providing unique insights specific to the Holstein breed compared to Jersey and Brown breeds.