Publications by authors named "M G Priore"
Among lyssaviruses, West Caucasian bat virus (WCBV) and Lleida bat lyssavirus (LLEBV) raise concern as their divergence from rabies virus leads to the inefficacy of available prophylactic agents. Both viruses were described in the bat . We investigated the European distribution of WCBV and LLEBV by screening sera from across eight countries, finding widespread serological evidence and positivity up to 70%.
View Article and Find Full Text PDFThe European subtype of tick-borne encephalitis virus (TBEV-Eur; species , family ) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species. Here, we report a tick-borne flavivirus isolated from Alpine chamois () with encephalitis and attached ticks, present over a wide area in the Alps. Cases were detected in 2017 in Salzburg, Austria, and 2023 in Lombardy and Piedmont, Italy.
View Article and Find Full Text PDFUnlabelled: The genus includes seventeen viral species able to cause rabies, an acute and almost invariably fatal encephalomyelitis of mammals. Rabies virus (RABV), which represents the type species of the genus, is a multi-host pathogen that over the years has undergone multiple events of host-switching, thus occupying several geographical and ecological niches. In contrast, non-RABV lyssaviruses are mainly confined within a single natural host with rare spillover events.
View Article and Find Full Text PDFArticle Synopsis
- Anthrax affects livestock, wildlife, and humans globally, but its impact on these populations is often underestimated, particularly regarding feral swine.
- A study involved invacuously inoculating feral swine with Sterne 34F2 spores to evaluate their immune response and potential role in spreading anthrax spores.
- Results showed that feral swine developed a dose-dependent antibody response and shed viable bacteria, indicating they could contribute to the spread of anthrax in the environment and pose risks to more susceptible species.
Article Synopsis
- Late-life psychiatric and neurological disorders (LLPND) often lead to ineffective drug treatments and adverse reactions due to age-related factors and variations in the cytochrome P450 (CYP) enzyme system, which is crucial for drug metabolism.
- Utilizing pharmacogenetics, specifically the genetics of CYP, could tailor drug therapies for common medications like antidepressants and antipsychotics, potentially reducing therapeutic failures and adverse drug reactions in older patients.
- This personalized approach aims to enhance patient outcomes, decrease drug dosages, minimize hospital readmissions, and ultimately lower healthcare costs related to LLPND management.