Publications by authors named "M G Patti"
Background: Evaluating individual health outcomes does not capture co-morbidities children experience.
Purpose: We aimed to describe profiles of child neurodevelopment and anthropometry and identify their predictors.
Methods: Using data from 501 mother-child pairs (age 3-years) in the Maternal-Infant Research on Environmental Chemicals (MIREC) Study, a prospective cohort study, we developed phenotypic profiles by applying latent profile analysis to twelve neurodevelopmental and anthropometric traits.
Obesity is a chronic disease that contributes to the development of insulin resistance, type 2 diabetes (T2D), and cardiovascular risk. Glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR) and glucagon-like peptide-1 (GLP-1) receptor (GLP-1R) co-agonism provide an improved therapeutic profile in individuals with T2D and obesity when compared with selective GLP-1R agonism. Although the metabolic benefits of GLP-1R agonism are established, whether GIPR activation impacts weight loss through peripheral mechanisms is yet to be fully defined.
View Article and Find Full Text PDFGastroesophageal reflux disease: indications for antireflux surgery, outcomes, and side effects.
Expert Rev Gastroenterol Hepatol
November 2024
Article Synopsis
- GERD is a common digestive disorder with various symptoms, but there's no clear global guideline on which patients should get anti-reflux surgery.
- The review looks at who might need surgery, what the surgery outcomes are, and the risks involved.
- While medication works for many, surgery might be essential for some patients to alleviate symptoms and avoid serious complications, emphasizing the importance of proper patient selection and informing them about potential side effects.
Context: Post-bariatric hypoglycemia (PBH) is a complication of bariatric surgery including Roux-en-Y gastric bypass (RYGB). It remains unclear why only some individuals develop PBH.
Objective: To identify clinical characteristics distinguishing post-RYGB individuals with PBH, versus without symptomatic hypoglycemia (RYGB non-hypo).