Publications by authors named "M G Ngari"
Introduction: Medicine quality can be influenced by environmental factors. In low- and middle-income countries (LMICs) with tropical climates, storage facilities of medicines in healthcare settings and homes may be suboptimal. However, knowledge of the effects of temperature and other climatic and environmental factors on the quality of medicines is limited.
View Article and Find Full Text PDFBackground: Links between early life exposures and child development later in life are not sufficiently explored in low- and middle-income countries. We studied associations between sociodemographic variables, growth and development at six to eight months with developmental outcomes at eight years.
Methods: We used data from a maternal education trial which included 511 mother-infant pairs at children's age of six to eight months (baseline).
Article Synopsis
- HEU (HIV-exposed uninfected) children face a higher risk of hospitalization and mortality compared to HUU (HIV-unexposed uninfected) children, prompting a closer look at their health outcomes.
- A study of 1486 children revealed that HEU children had significantly higher rates of hospitalization mortality and were more prone to wasting and stunting.
- Despite similar illness severity and resource use in hospitals, HEU children had longer stays and a two-fold increased risk of dying within 30 days of hospitalization compared to HUU peers.
In sub-Saharan Africa, children with severe malnutrition (SM) and HIV have substantially worse outcomes than children with SM alone, facing higher mortality risk and impaired nutritional recovery post-hospitalisation. Biological mechanisms underpinning this risk remain incompletely understood. This case-control study nested within the CHAIN cohort in Kenya, Uganda, Malawi, and Burkina Faso examined effect of HIV on six months post-discharge growth among children with SM and those at risk of malnutrition, assessed proteomic signatures associated with HIV in these children, and investigated how these systemic processes impact post-discharge growth in children with SM.
View Article and Find Full Text PDFArticle Synopsis
- The study examines the prevalence of different forms of undernutrition (wasting, underweight, and stunting) in children aged 6-59 months hospitalized in Garissa County, Kenya, between 2017 and 2019.
- Out of 624 hospitalized children, 95% had wasting, 83% were underweight, and 28% were stunted, with significant overlap between these conditions.
- Key risk factors included diarrhea, which was associated with wasting and stunting, and anemia linked to wasting and underweight; the overall inpatient death rate was notably high at 8%.