Publications by authors named "M G Minasi"

Article Synopsis
  • - The search for reliable markers to evaluate oocyte quality and its impact on embryonic development has been challenging, with no universally accepted criteria for oocyte competence as advanced maternal age is a significant factor, but numerous other influences exist.
  • - Factors like obesity, lifestyle, genetic issues, ovarian stimulation, and environmental conditions all potentially affect oocyte quality, with morphological evaluations being the most common method for assessing reproductive potential.
  • - While some abnormalities in oocytes may indicate lower developmental potential, no single issue is predictive enough, and many innovative techniques are still in research phases rather than clinical use, leading to a lack of consistent methods for assessing oocytes.
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Article Synopsis
  • Time-lapse systems (TLSs) for embryo incubation have evolved significantly, moving from traditional incubators to more suitable benchtop models for human IVF.
  • Advances in imaging technology and developments in wireless and smartphone tech have made TLSs more accessible for both labs and patients, enhancing user experience.
  • The review discusses the history, available TLSs, clinical results, and limitations of this technology in modern IVF laboratories.
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In 2002 we published an article describing a population of vessel-associated progenitors that we termed mesoangioblasts (MABs). During the past decade evidence had accumulated that during muscle development and regeneration things may be more complex than a simple sequence of binary choices (e.g.

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Study Question: Can the possibility of having at least one euploid blastocyst for embryo transfer and the total number of euploid blastocysts be predicted for couples before they enter the IVF programme?

Summary Answer: Ovarian reserve and female age are the most important predictors of having at least one euploid blastocyst and the total number of euploid blastocysts.

What Is Known Already: The blastocyst euploidy rate among women undergoing ART has already been shown to significantly decrease with increasing female age, and the total number of euploid embryos is dependent on the blastocyst cohort size. However, the vast majority of published studies are based on retrospective analysis of data.

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