Publications by authors named "M G McGrady"

Article Synopsis
  • This study investigates the effectiveness of monetary incentives in improving adherence to obesity treatment among adolescents.
  • Sixty adolescents were divided into three groups: Gain Group (GG) received rewards for achieving adherence goals, Loss Group (LG) lost funds for failing to meet goals, and Control Group (CG) received a fixed amount monthly.
  • Results showed that the GG had significantly higher adherence scores and achieved more dietary reporting and step goals compared to the LG and CG, indicating that gain-framed incentives are more effective than loss-framed ones.
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Article Synopsis
  • Tissues are made up of units that can be studied at various scales, and new tech helps researchers analyze their structure and function in-depth.
  • The article introduces a method called spatial cellular graph partitioning (SCGP) for automatically annotating tissue structures without manual input, making it more efficient.
  • SCGP, along with its reference-query extension, shows strong accuracy in identifying tissue structures and offers valuable insights into diseases like diabetic kidney disease and skin disorders.
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Aims/hypothesis: Diabetic kidney disease (DKD) is the leading cause of chronic and end-stage kidney disease in the USA and worldwide. Animal models have taught us much about DKD mechanisms, but translation of this knowledge into treatments for human disease has been slowed by the lag in our molecular understanding of human DKD.

Methods: Using our Spatial TissuE Proteomics (STEP) pipeline (comprising curated human kidney tissues, multiplexed immunofluorescence and powerful analysis tools), we imaged and analysed the expression of 21 proteins in 23 tissue sections from individuals with diabetes and healthy kidneys (n=5), compared to those with DKDIIA, IIA-B and IIB (n=2 each) and DKDIII (n=1).

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Objective: This meta-analysis examined the efficacy of adherence-promotion interventions for children, adolescents, and young adults prescribed a medication for > 90 days as part of a treatment regimen for a medical condition.

Methods: A systematic literature review was conducted to identify randomized controlled trials of adherence-promotion interventions published between 2013 and 2023 and including children, adolescents, and/or young adults with a medical condition. A total of 38 articles representing 39 trials met inclusion criteria.

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This cross-sectional study described prevalent body image (BI) concerns among adolescents and young adults (AYAs) with neoplasms who received treatment at a quaternary care children's hospital. Thirty-two AYAs, aged 15-39 years, completed questionnaires assessing BI within six months of diagnosis. The most frequently endorsed questionnaire items included the following: desire for increased physical fitness (62.

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