Aging-induced changes in lymphatic muscle cell transcriptomes are associated with reduced pumping of peripheral collecting lymphatic vessels in mice.

Lymphatic muscle cells (LMCs) within the wall of collecting lymphatic vessels exhibit tonic and autonomous phasic contractions, which drive active lymph transport to maintain tissue-fluid homeostasis and support immune surveillance. Damage to LMCs disrupts lymphatic function and is related to various diseases. Despite their importance, knowledge of the gene transcriptional signatures in LMCs and how they relate to lymphatic function in normal and disease contexts is largely missing.

Improving Patient Handoffs and Transitions in Care Among Residents: A Chief Resident-Led Initiative.

Introduction: Effective handoff between pediatric residents is crucial to ensure continuity of care and patient safety. Omissions in information and communication breakdowns can be associated with uncertainty in clinical decision-making and adverse patient events. In our role as chief residents, we were notified of an increase in patient safety alerts due to communication failures and gaps during handoff.

Efficacy of a Mobile App-Based Behavioral Intervention (DRIVEN) to Help Individuals With Unemployment-Related Emotional Distress Return to Work: Protocol for a Randomized Controlled Trial.

Background: Employment plays an important role in the maintenance of mental and physical health. Losing a job creates emotional distress, which can, in turn, interfere with effective job seeking. Thus, a program for job seekers that provides support for both the logistics of job seeking as well as emotional distress may help people find employment and improve emotional well-being.

Eco-friendly extracts for corrosion protection of steel in acidic environments.

This study evaluates the potential of Chlorella vulgaris sp. extracts as eco-friendly corrosion inhibitors for API 5L 42 Steel in a 1M HCl acidic environment, offering sustainable alternatives for industrial applications. Two corrosion inhibitors were obtained through solvent extraction methods: M1 (methanol) and M2 (methanol/chloroform).