Publications by authors named "M G Malaise"
Background: Identifying remission is of high importance in rheumatoid arthritis (RA) because remission is associated with less structural progression. We investigated the efficacy of a new optical imaging device, HandScan, to identify RA remission, as defined by ultrasound (US).
Methods: 61 RA patients were included.
Systemic sclerosis (SSc) is a rare autoimmune disease in which interstitial lung disease (ILD) is the leading cause of morbidity and mortality. Clinical management of the lung disease is mainly based on pulmonary function testing (PFT) and their changes over time. Little is known about the reproducibility of PFT testing in SSc patients.
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- Pulmonary fibrosis is a serious complication resulting from SARS-CoV-2 infection, and this study examines whether patients with COVID-19 and idiopathic pulmonary fibrosis (IPF) share similar microRNA (miRNA) expressions linked to lung fibrosis.
- The research involved a systematic review of literature from 2010 to January 2022, identifying 34 overlapping miRNAs between COVID-19 and IPF, with some exhibiting upregulation and others downregulation.
- Findings indicate that elevated levels of profibrotic miRNAs and an imbalance in antifibrotic miRNAs contribute to the development of lung fibrosis in patients recovering from COVID-19.
Unlabelled: Chronic obstructive pulmonary disease (COPD) is a risk factor for osteoporosis. Our objective is to determine if functional indices associated with emphysema on pulmonary function tests (DLCO-diffusion capacity of the lung for CO-; DLCO/AV-DLCO corrected for alveolar volume- and TLC-total lung capacity), considered alone or together, can identify COPD patients with osteoporosis.
Methods: 90 COPD patients underwent dual-energy X-ray absorptiometry (DEXA) and pulmonary function tests.
Objectives: In our study, we explored the specific subgroup of patients with rheumatoid arthritis (RA) suffering from obstructive lung disease (OLD) and its impact on morbi-mortality.
Methods: Our retrospective study included 309 patients suffering from RA with either obstructive (O-RA) or non-obstructive patterns (non-O-RA). OLD was defined based on the Tiffeneau index at the first available pulmonary functional test (PFT).