Publications by authors named "M G Lebrette"
Unlabelled: We evaluated an elvitegravir-cobicistat-emtricitabine-tenofovir alafenamide single-tablet regimen for human immunodeficiency virus postexposure prophylaxis. The completion rate and adherence were good, and the tolerance was acceptable; no seroconversion was observed. We confirm that this regimen could be appropriate for postexposure prophylaxis.
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- * A study of 694 HIV-infected outpatients found that 14% had PTD, but common diagnostic markers were ineffective in accurately identifying it.
- * Tenofovir disoproxil fumarate exposure was linked to PTD primarily in non-African patients, with only a small percentage experiencing a rapid decline in estimated glomerular filtration rate (eGFR) over time.
Objective: To assess the characteristics and outcomes of patients with AIDS-related primary CNS lymphoma (AR-PCNSL) in the combined antiretroviral therapy (cART) era systematically treated with high-dose methotrexate (HD-MTX).
Methods: We retrospectively analyzed (intention-to-treat analysis) 51 consecutive patients with AR-PCNSL (median age 39 years) who were diagnosed from 1996 to 2014 and treated with a median of 6 (range 1-15) infusions of HD-MTX (3 g/m) combined with cART.
Results: Median all-patients' and survivors' follow-up lasted 23 (range 0-186) and 76 (range 23-186) months, respectively.
Article Synopsis
- The study examines the factors associated with viral failure in HIV-positive infants born in France, focusing on maternal psychological issues and the children's environment.
- Out of 1061 infants followed, 14 were diagnosed with HIV before age 1, with differences in viral control linked to the mothers' mental health, particularly severe psychological disorders.
- The findings emphasize that maternal mental health significantly impacts treatment adherence and the risk of mother-to-child transmission of HIV, suggesting a need for greater support for affected families.
Background: Body piercing has become widespread and is associated with increased complications. Post-piercing chondritis may lead to severe residual deformity. We aimed to report case patients presenting with post-piercing chondritis in our department and to describe clinical features and treatment.
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