Non-thermal atmospheric plasma treatments enhance the growth, photosynthesis, metabolite accumulation, and nutritional value of geranium (Pelargonium graveolens L'Herit) leaves.

This study investigated the effects of non-thermal atmospheric plasma (NTAP) treatment on the growth, chemical composition, and biological activity of geranium (Pelargonium graveolens L'Herit) leaves. NTAP was applied at a frequency of 13.56 MHz, exposure time of 15 s, discharge temperature of 25 °C, and power levels (T1 = 50, T2 = 80, and T3 = 120 W).

Granisetron ameliorates doxorubicin-evoked nephrotoxicity via modulation of Nrf2 and TLR4/p38 MAPK/NLRP3 signals in rats.

Doxorubicin (DOX) is an anthracycline chemotherapy employed in treating malignancies. Unfortunately, the clinical application of DOX is limited due to its nephrotoxicity. Granisetron (GRAN) is a 5-HT3 receptor blocker used widely to manage post-chemotherapy nausea and vomiting with anti-inflammatory, anti-oxidant, and anti-apoptotic bioactivities.

Investigation of the optimum calcination temperature for water treatment plant sludge to develop a sustainable alkali activated concrete.

Nowadays, Egypt is treating the Nile River Water to produce drinking water, and this process generates large amounts of waste, around 635 million m annually, which is called water treatment plant sludge (WTPS). This WTPS cost the government around 30 million US dollars to return it back to the Nile River in addition to negatively affecting the environment. Therefore, there is an urgent need to find environmentally friendly alternatives that reduce the impact of such an issue.

Repurposing bosentan as an anticancer agent: EGFR/ERK/c-Jun modulation inhibits NSCLC tumor growth.

Drug repurposing of well-established drugs to be targeted against lung cancer has been a promising strategy. Bosentan is an endothelin 1 (ET-1) blocker widely used in pulmonary hypertension. The current experiment intends to inspect the anticancer and antiangiogenic mechanism of bosentan targeting epidermal growth factor receptor (EGFR) /extra-cellular Signal Regulated Kinase (ERK) /c-Jun/vascular endothelial growth factor (VEGF) carcinogenic pathway.

Formulation of sustainable, biodegradable chitosan films enriched with Origanum majorana extract as an eco-friendly antimicrobial food packaging for possible food preservation.

In this work, chitosan (Cs) was blended with different concentrations of Origanum majorana extract (OmE) that extracted using ethyl acetate and used for the formation of food packaging films. Based on the utilized volumes of OmE (2.5, 5, and 7.