Publications by authors named "M G J Balvers"
Article Synopsis
- The study introduces a new smartphone-based 2-hour recall method (2hR) for dietary assessment, aiming to reduce memory bias and respondent burden compared to traditional methods like the FFQ (Food Frequency Questionnaire).
- Conducted on 215 Dutch adults over four weeks, the study found that 2hRs provided slightly higher energy intake estimates and showed moderate to strong correlations with both FFQ and blood concentration markers of nutrients like carotenoids and n-3 PUFA.
- Overall, the 2hR method demonstrated good ranking ability for assessing dietary intake and was effective in classifying participants' nutrient and food group consumption similarly to the FFQ and blood analyses.
Hypothalamic inflammation often coincides with cancer and cachexia-anorexia. Prior work established the significance of tumor-derived inflammatory factors in triggering hypothalamic inflammation, yet the precise mechanisms remained elusive. Here, we demonstrate that prostaglandin E2 (PGE2), produced in the tumor via cyclooxygenase-2 (COX-2), plays a pivotal role in this context.
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- The study examines how gut health markers vary within the same individuals over time, highlighting that this variability is not well understood despite advancements in gut health research.
- A total of ten healthy adults provided faecal samples across three consecutive days, resulting in specific variability percentages for different gut health markers, revealing significant differences in consistency and bacterial counts.
- An improved processing method, involving mill-homogenization of frozen faeces, decreased variability in certain markers without changing their average levels, suggesting that repeated sampling might be necessary for accurate gut health analysis.
Background: Vitamin K is essential for numerous physiological processes, including coagulation, bone metabolism, tissue calcification, and antioxidant activity. Deficiency, prevalent in critically ill ICU patients, impacts coagulation and increases the risk of bleeding and other complications. This review aims to elucidate the metabolism of vitamin K in the context of critical illness and identify a potential therapeutic approach.
View Article and Find Full Text PDFAims/hypothesis: Use of genetic risk scores (GRS) may help to distinguish between type 1 diabetes and type 2 diabetes, but less is known about whether GRS are associated with disease severity or progression after diagnosis. Therefore, we tested whether GRS are associated with residual beta cell function and glycaemic control in individuals with type 1 diabetes.
Methods: Immunochip arrays and TOPMed were used to genotype a cross-sectional cohort (n=479, age 41.