Publications by authors named "M G Grimoldi"

Background: Transversus abdominis release (TAR) is an effective technique for treating large midline and off-midline hernias. Recent studies have demonstrated that robotic TAR (rTAR) is technically feasible and associated with improved outcomes compared to open surgery. There is no published experience to date describing abdominal wall reconstruction using the novel robotic platform HUGO RAS System (Medtronic®).

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Article Synopsis
  • A study involving 68 multiple sclerosis patients treated with alemtuzumab tracked the production of T and B lymphocytes over a 48-month period.
  • Initially, new T lymphocyte levels dropped significantly three months after treatment, but by 36 months, they peaked, indicating a strong recovery of thymic function.
  • B cell production also increased, exceeding baseline levels as soon as three months after starting the treatment, with variations in cellular recovery patterns unrelated to factors like age, sex, previous treatments, or disease outcomes.
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Background And Objectives: A variety of neurologic disorders have been reported as presentations or complications of coronavirus disease 2019 (COVID-19) infection. The objective of this study was to determine their incidence dynamics and long-term functional outcome.

Methods: The Neuro-COVID Italy study was a multicenter, observational, cohort study with ambispective recruitment and prospective follow-up.

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Background: Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is associated with disorders affecting the peripheral and the central nervous system. A high number of patients develop post-COVID-19 syndrome with the persistence of a large spectrum of symptoms, including neurological, beyond 4 weeks after infection. Several potential mechanisms in the acute phase have been hypothesized, including damage of the blood-brain-barrier (BBB).

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Large hernia defects are a challenge for general and specialized hernia surgeons. The release (TAR) technique has revolutionized the treatment of complex hernias since it allows the closure of large midline hernias, as well as hernias in different locations. This study aims to report the experience with the TAR technique and mid-term results in the first 101 patients.

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