Publications by authors named "M G Gonchar'"
We report the development of amperometric biosensors (ABSs) employing flavocytochrome (Fc) coupled with nanoparticles (NPs) of noble metals on graphite electrode (GE) surfaces. Each NPs/GE configuration was evaluated for its ability to decompose hydrogen peroxide (HO), mimicking peroxidase (PO) activity. The most effective nanoPO (nPO) was selected for developing ABSs targeting L-lactate.
View Article and Find Full Text PDFMonitoring of the levels of 5-hydroxyindole-3-acetic acid (5-HIAA) is of significant importance for diagnostics of carcinoid tumors. We propose simple catalytic electrochemical sensors for the determination of 5-HIAA in urine using laccase and its mimetics. Laccase-like nanozymes (LacNZs) were synthesized via a chemical reduction, and resulting PtMn and MnO nanoflowers (NFs) demonstrated laccase-like activity similar to the laccase from the Trametes zonata.
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- - The Daya Bay experiment has successfully measured the oscillation amplitude and frequency of reactor antineutrinos over nearly 2,000 days of data, finding significant results about their behavior.
- - They observed over 3.6 million signal candidates using improved selection and calibration methods, leading to a measurement of sin²2θ₁₃ = 0.0759 with a precision that indicates how antineutrinos change states.
- - Combining results from different detection methods at Daya Bay, the overall measurement of sin²2θ₁₃ increased precision to 0.0833±0.0022, representing an 8% improvement in understanding these neutrino properties.
This study aims to design microgels for controlled drug release via enzymatically generated pH changes in the presence of glucose. Modern medicine is focused on developing smart delivery systems with controlled release capabilities. In response to this demand, we present the synthesis, characterization, and enzymatically triggered drug release behavior of microgels based on poly(acrylic acid) modified with glucose oxidase (GOx) (p(AA-BIS)-GOx).
View Article and Find Full Text PDFThis Letter presents results of a search for the mixing of a sub-eV sterile neutrino with three active neutrinos based on the full data sample of the Daya Bay Reactor Neutrino Experiment, collected during 3158 days of detector operation, which contains 5.55×10^{6} reactor ν[over ¯]_{e} candidates identified as inverse beta-decay interactions followed by neutron capture on gadolinium. The analysis benefits from a doubling of the statistics of our previous result and from improvements of several important systematic uncertainties.
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