Publications by authors named "M G Drabkina"
Article Synopsis
- - The research explores how coinfections with HPV16 and Chlamydia affect the cervical mucosa, utilizing patient-derived ectocervical organoids to mimic the cervical environment, which has previously limited the study of these interactions.
- - Genetic manipulation of ectocervical stem cells created models that exhibit characteristics of precancerous lesions while still retaining their ability to develop into mature tissue, showing how HPV16 alters Chlamydia's behavior.
- - The study reveals that Chlamydia not only disrupts HPV-induced cellular health mechanisms but also suggests that the unique interactions between these infections may contribute to an increased risk of cervical cancer.
Article Synopsis
- The squamous and columnar epithelia are areas in the cervix that can develop cancer, often starting with a process called metaplasia, where one type of cell is replaced by another.
- Researchers used advanced technology to study the different types of cells in these areas, discovering that they come from different types of stem cells that are controlled by opposite signals from surrounding tissue.
- In experiments with mice, they found that changes in the tissue can lead to increased growth of certain stem cells, showing how the balance of cells at the transition zone is influenced by different signals in the tissue around them.
[Development of a system for medico-social rehabilitation of industrial workers].
Probl Sotsialnoi Gig Istor Med
January 1999