Publications by authors named "M G De Nuzzo"
Article Synopsis
- Acute gastroenteritis (AGE) is a sickness caused by bad food or water that can make kids very sick and sometimes need hospital care.
- A study looked at 103 kids aged 0 to 15 who were treated for AGE at a hospital in Lecce, Italy, and found that most of the infections were caused by viruses and bacteria.
- Young children under 5 were more likely to get really dehydrated from AGE, and preventing it could get better with cleaner food and water, plus more vaccines.
Article Synopsis
- The study investigates the effectiveness and economic benefits of using dalbavancin for treating acute bacterial skin infections compared to standard treatments, highlighting the potential for early patient discharge.
- It analyzed data from patients treated with dalbavancin at a hospital in Italy over six years, demonstrating its role in reducing hospital stays and improving antibiotic adherence.
- Findings suggest that dalbavancin can save over €3,200 per patient by facilitating quicker discharges while managing complex infections effectively.
Introduction: Randomized clinical trials (RCTs) represent the mainstay for the approval of new treatments. However, stringent inclusion criteria often cause them to depart from the daily clinical practice. Real-world (RW) evidence have a complementing role, filling the gap between the efficacy of a treatment and its effectiveness.
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- The study reviewed complications from percutaneous ethanol injection (PEI) for benign and cystic thyroid nodules, combining data from 48 published studies and an additional 3670 cases from a specific hospital in Italy.
- The overall prevalence of complications was found to be 32%, with the majority categorized as minor (32%) and major complications being rare (2%).
- Most complications, such as local pain (21%) and transient dysphonia (1%), were considered mild and often required minimal or no treatment.
Sex-related differences in serum biomarker levels predict the activity and efficacy of immune checkpoint inhibitors in advanced melanoma and non-small cell lung cancer patients.
J Transl Med
March 2024
Background: Immune Checkpoint Inhibitors (ICIs) lead to durable response and a significant increase in long-term survival in patients with advanced malignant melanoma (MM) and Non-Small Cell Lung Cancer (NSCLC). The identification of serum cytokines that can predict their activity and efficacy, and their sex interaction, could improve treatment personalization.
Methods: In this prospective study, we enrolled immunotherapy-naïve patients affected by advanced MM and NSCLC treated with ICIs.