Reliability of core needle biopsy for HER2-low early-stage breast cancer.

Background: The reliability of core needle biopsy (CNB) for HER2-positive breast cancer is well established. However, data on HER2-low and the potential for inconsistencies with surgical samples are limited.

Materials And Methods: Concordance between CNB and surgical samples was assessed using the unweighted Cohen kappa statistic (Kc) in a consecutive series of 776 treatment-naïve early-stage breast cancer patients.

[Physical activity in people with borderline personality disorder: a study protocol for a randomised controlled trial.].

Purpose: Treatments for mental disorders, such as pharmacotherapy and psychosocial interventions, do not always guarantee symptomatic remission. The effectiveness of Physical Activity (PA) in improving the psychophysical health of individuals with various mental disorders is well-established; however, its effects on borderline personality disorder (BPD) have yet to be adequately studied. Currently, there are not approved pharmacological treatments for BPD, and access to effective psychotherapeutic interventions remains limited.

Isolation of Acanthamoeba Species and Bacterial Symbiont Variability in Puna Salt Plains, Argentina.

Acanthamoeba spp. are widespread protists that feed on bacteria via phagocytosis. This predation pressure has led many bacteria to evolve strategies to resist and survive inside these protists.

Recent Advances and Current Challenges in Stereotactic Body Radiotherapy for Ultra-Central Lung Tumors.

Stereotactic body radiotherapy has been established as a viable treatment option for inoperable early-stage non-small cell lung cancer or secondary lesions mainly in oligoprogressive/oligometastatic scenarios. Treating lesions in the so-called "no flight zone" has always been challenging and conflicting data never cleared how to safely treat these lesions. This is truer considering ultra-central lesions, i.

Treatment of oligometastatic breast cancer: The role of patient selection.

Up to 90 % of death from solid tumors are caused by metastases. By 2040, breast cancer (BC) is predicted to increase to over 3 million new cases. Additionally, with the personalization and intensification of BC follow-up, many patients will relapse with oligometastatic disease (OMD).