Clin Pract Epidemiol Ment Health
August 2024
Background: Internet gaming disorder is defined as "Persistent and recurrent use of the internet to engage in games, often with other players, leading to clinically significant impairment or distress." It is a new evolving disorder that affects many life aspects; therefore, it needs further investigation among different population groups. IGD was introduced for the first time in 2013 in the fifth edition of the , and it suggested carrying out further research among different populations.
View Article and Find Full Text PDFAim: The main indications for Ahmed glaucoma valve (AGV) include neovascular glaucoma, congenital glaucoma, primary open angle glaucoma and patients with failed previous trabeculectomy. This article aims to investigate the complications of AGV in Jordanian glaucoma patients and to justify the main risk factors.
Methods: Retrospectively, we report 87 eyes of 83 patients who underwent AGV implantation for different indications.
Speckle-type POZ (SPOP) is described as an essential tumor suppressor factor in gastric cancer, colorectal cancer, and prostate cancer (PCa). SPOP gene mutations were reported in primary human PCa. Isocitrate dehydrogenase-1 (IDH1) oncogene mutations were detected in gliomas, acute myeloid leukemia, some benign and malignant cartilaginous tumors, and only 1% of PCa.
View Article and Find Full Text PDFBackground: There are limited and conflicting data regarding the impact of race or ethnicity on the rate of gram-negative antimicrobial resistance. This study was performed to determine whether there is a difference in extended-spectrum beta-lactamase (ESBL) infection or colonization in minoritized patients when compared to White patients from a diverse US Midwestern city.
Methods: A case control study was performed, with controls with non-ESBL matched 1:1 to patients with ESBL-producing based on age, sex, and ZIP code.
Curr Issues Mol Biol
September 2024
The oncogene is related to various cancers due to its critical role in the PIC3CA/AKT1 pathway; however, most of the studies screened the hotspot mutation (E17K) with various incidences. Low frequency or lack of (E17K) mutation was reported in prostate cancer (PC) patients. This study aims to explore genetic alterations in the AKT1 PH domain by extending the sequencing to include gene exons 3 and 4.
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