Publications by authors named "M Fuoti"
Treatment with an ileal bile acid transporter inhibitor in patients with TJP2 deficiency.
Clin Res Hepatol Gastroenterol
October 2023
There are no published data on the use of odevixibat, a selective ileal bile acid transporter (IBAT) inhibitor, in children with tight junction protein 2 (TJP2) deficiency (also named as PFIC-4). We describe a case series of five children treated with odevixibat. After treatment, serum bile acids (sBA) decreased compared to baseline [mean value: 244 (±125), vs 38 (±34) µmol/L; p = 0.
View Article and Find Full Text PDFBackground: The natural history of ulcerative proctitis (UP) has been poorly investigated in children.
Aims: We aimed to compare the disease course of children with UP at diagnosis to the other locations and to identify extension predictors.
Methods: This was a multicenter, observational study carried out from data prospectively entered in the SIGENP-IBD-Registry.
Article Synopsis
- * A group of experts worked together to gather information on how to diagnose NIC by studying different sources and using a special scoring system to rate the evidence.
- * Their recommendations on how to best diagnose NIC in babies were approved by a majority of the experts and put together in a final document.
Improving the quality of life (QoL) is crucial in the management of pediatric inflammatory bowel disease (IBD). We aimed to (1) Validate the IMPACT-III questionnaire in Italian IBD children; (2) explore factors associated to QoL in pediatric IBD. Internal consistency, concurrent validity, discriminant validity and reproducibility of the Italian version of the IMPACT-III questionnaire was measured in IBD children/adolescents in 8 centers.
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