Publications by authors named "M Fujikawa"

The crustacean Daphnia magna is an emerging model for ecological and toxicological genomics. However, the lack of methods for spatial and temporal control of gene expression has impaired the elucidation of molecular mechanisms underlying responses to environments in vivo. Here we report local activation of the hsp70 promoter-driven gene cassette in D.

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Background: Predicting posthepatectomy liver failure (PHLF) may be a critical requirement for liver disease patients undergoing hepatectomy. This study retrospectively analyzed the impact of the intraoperatively measured portal vein pressure (PVP) prior to hepatectomy on the prediction of PHLF in hepatectomized patients.

Methods: A total of 334 hepatectomized patients in whom the PVP was intraoperatively measured before resection at our institution were enrolled in the present study.

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  • The study explored the complex decision-making process involved in disclosing epilepsy in the workplace, examining both the benefits and drawbacks of such disclosures.
  • Researchers analyzed data from 193 patients who underwent extensive assessments at a hospital's Epilepsy Monitoring Unit, focusing on various predictive factors related to the decision to disclose.
  • Results showed that 43.5% of patients chose to disclose their condition, with key influencing factors including experiences of discrimination and having witnessed their own seizures, as well as levels of enacted stigma.
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  • A study re-evaluated potassium iodide (KI) therapy for treating Graves' hyperthyroidism (GD) due to adverse effects linked to thionamide medications.
  • 324 untreated GD patients were given 100 mg/day of KI, and results showed a significant decrease in thyroid hormone levels within weeks, with over 50% of patients maintained on KI remaining well-controlled over two years.
  • No adverse effects were reported from KI, highlighting its effectiveness as a treatment option, with 42.7% of patients achieving consistent control of their condition.
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To present the background, rationale, details pertaining to use and essential computational steps, synopsis of findings to date, and future directions for the International Classification of Cognitive Disorders in Epilepsy (IC-CoDE)-an initiative of the ILAE Neuropsychology Task Force. Examined are: (a) the 6 steps leading to the derivation of a cognitive phenotype from neuropsychological test data with an accompanying case example, (b) concise review of all IC-CoDE research to date, (c) summary of identified correlates of IC-CoDE outcomes, and (d) future research and clinical directions for the initiative. The IC-CoDE is computationally uncomplicated with individual or group data and represents a novel approach leading to new insights in the neuropsychology of epilepsy, with applications to diverse datasets internationally informing the reliability and validity of the approach.

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