Publications by authors named "M Fuat Acıkalın"
Purpose: Reinke's edema is a benign lesion affecting the subepithelial layer of the vocal cords, often associated with moderate or heavy smoking. Smoking is the most significant risk factor for dysplastic laryngeal lesions, laryngeal carcinomas, and Reinke's edema. Thus, Reinke's edema could potentially be a predisposing factor for laryngeal malignancy in the long term.
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- Mucosal melanomas, particularly in the oral and sinonasal regions, present diagnostic challenges due to their varied characteristics and differentiation patterns, including neuroendocrine features.
- A study of 18 cases revealed that 72.2% displayed neuroendocrine differentiation, suggesting it is a common feature in these types of melanoma.
- The research highlights the importance of recognizing neuroendocrine markers (like synaptophysin, chromogranin, CD56, and INSM-1) in preventing misdiagnoses in malignant melanomas.
Article Synopsis
- Cutaneous melanoma frequently spreads to the parotid glands, but there's limited research on using fine-needle aspiration (FNA) to diagnose these metastatic cases.
- This study examined four patients with parotid masses, revealing atypical cells and other features through FNA and immunohistochemical tests.
- The findings highlight that diagnosing melanoma in such cases can be difficult without a prior history, necessitating careful consideration and additional testing to confirm the diagnosis.
Objectives: Cribriform glands are linked to poorer outcomes in prostate adenocarcinoma. We aimed to assess the prognostic role of the percentage of cribriform glands and the size of the largest invasive cribriform gland in Gleason score 7 prostate adenocarcinomas.
Methods: The presence, percentage, and size of the invasive cribriform glands were investigated and their association with prognostic factors were assessed in 177 Grade Groups 2 and 3 prostate adenocarcinomas.
Background: We investigated the role of European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) classification criteria for the prediction of LN among children with SLE.
Methods: The data of the patients with childhood-onset SLE diagnosed based on 2012 Systemic Lupus International Collaborating Clinics (SLICC) criteria were retrospectively evaluated. Based on 2019 EULAR/ACR classification criteria, the scoring was done at the time of renal biopsy.