In Vitro Antibacterial Activity, Molecular Docking, and ADMET Analysis of Phytochemicals from Roots of .

is widely used in Ethiopia for treating various human ailments, yet its pharmacological properties and chemical composition remain largely unexplored. The chromatographic separation of roots extract afforded five compounds, namely tremulacin (), cochinchiside A (), 5-methoxydurmillone (), catechin-7--α-L-rhamnopyranoside (), and stigmasterol (), confirmed via IR, NMR, and MS spectral data. This is the first report of these compounds from this plant, except for compounds and .

The first fossil longhorn beetles (Coleoptera: Cerambycidae) from Australia.

Longhorn beetles (family Cerambycidae) are globally distributed insects with important ecological roles. Here we present the first discovery of fossil longhorn beetles from Australia. The two new taxa described, Ventiala beattiei gen.

Cry1 resistance in a CRISPR/Cas9-mediated HaCad1 gene knockout strain of the Australian cotton bollworm Helicoverpa armigera conferta (Lepidoptera: Noctuidae).

Background: Helicoverpa armigera is a highly polyphagous species that causes huge losses to agricultural and horticultural crops worldwide. In the cotton industry, H. armigera, including the Australian subspecies Helicoverpa armigera conferta, is largely managed using genetically modified crops that express insecticidal toxins, such as Cry1Ac.

Cytotoxic clerodane diterpenoids from the roots of Mast.

A study of diterpenoids as active ingredients against cancer from the active roots extract of Mast. (IC = 1.57 μg mL) led to the isolation of six new clerodane diterpenoids, named as barterins A-F (1-6) alongside seven known compounds, caseamembrin A, caseamembrin E, casearlucin A, graveospene G, -feruloyltyramine, -feruloytyramine and sitosterol-3--β--(6--palmitoyl)-glucopyranoside.

Hepatobiliary organoids derived from leporids support the replication of hepatotropic lagoviruses.

The genus of the family contains some of the most virulent vertebrate viruses known. Lagoviruses infect leporids, such as rabbits, hares and cottontails. Highly pathogenic viruses such as (RHDV1) cause a fulminant hepatitis that typically leads to disseminated intravascular coagulation within 24-72 h of infection, killing over 95 % of susceptible animals.