Intraocular silicone implant to treat chronic ocular hypotony-preliminary feasibility data.

Purpose: Ocular hypotony secondary to proliferative vitreoretinopathy-related retinal detachment, trauma or inflammation is difficult to treat. Besides endotamponades such as silicone oil, vitreous implants such as iris diaphragms or balloons have been developed to stabilize the eye and to prevent phthisis of the globe. Vitreous implants tested thus far exhibit a seam at the attachment site of the hemispheres, or micropores.

The Ex Vivo Eye Irritation Test (EVEIT) in evaluation of artificial tears: Purite-preserved versus unpreserved eye drops.

Objective: Preservatives in artificial tears cause controversy. New developments such as the Purite system have been introduced into the market, with the promise of little damage to the corneal surface. We wanted to give insight into the differences in the effect of preserved and unpreserved artifical tears on rabbit corneas cultured with the Ex Vivo Eye Irritation Test (EVEIT) system.

[Eye irritation and chemical eye burns. Review of experimental and clinical studies].

Chemical burns of the eye are becoming rare due to improvements in occupational protection. Effective decontamination is the foundation for good clinical results of this ophthalmological emergency. The toxicological aspect focuses on classifying the specific toxicity of a chemical substance by evaluating the degree of eye irritation and eye burns.

Changing the composition of buffered eye-drops prevents undesired side effects.

Purpose: The Ex Vivo Eye Irritation Test (EVEIT) is used to analyse the clinical observations of corneal calcification attributed to the presence of phosphate within applied eye-drops used in treating glaucoma, Still-Chauffard syndrome, ocular burns and dry eyes.

Method: Live corneas from abattoir rabbit eyes were cultured in order to study epithelial healing following mechanical abrasion of the corneal surface combined with repeated exposure to various eye-drops.

Results: Obvious corneal calcification of the wound area along with a complete epithelial healing covering the calcified area was observed following exposure to phosphate hyaluronate eye-drops.