Publications by authors named "M Fracaro"
Article Synopsis
- Susac syndrome, multiple sclerosis, and primary angiitis of the central nervous system often present similar symptoms, making accurate diagnosis a challenge; the study aimed to improve this through a new scoring system called the SPAMS score.
- The research involved 99 patients from South America and utilized an elastic-net model to determine important MRI features for distinguishing between these conditions.
- The SPAMS score demonstrated high diagnostic accuracy, effectively differentiating SuS from MS and PACNS, highlighting the importance of specific MRI findings for timely interventions and potentially better patient outcomes.
Unlabelled: The objective of the study was to evaluate the incidence of COVID-19 after complete vaccination in people with multiple sclerosis (PwMS) included in the Argentinean MS and NMOSD registry (RelevarEM, NCT03375177).
Methods: cohort study conducted between May 2021 and December 2021. The primary outcome was the appearance of infection during the follow-up time (at least three months after complete vaccination (second dose)).
Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis?
Mult Scler Relat Disord
February 2022
Background: In multiple sclerosis demographics there is a well-known female prevalence and male patients have been less specifically evaluated in clinical studies, though some clinical differences have been reported between sexes.
Objective: The objective of this study was to assess clinical and demographic differences between male and female patients included in the national Argentine MS Registry-RelevarEM.
Material And Methods: This study was observational, retrospective, and was based on the data of 3099 MS patients included as of 04 April 2021.
Unlabelled: The objectives of the present study were to describe the frequency of aggressive multiple sclerosis (aMS) as well as to compare clinical and radiological characteristics in aMS and non-aMS patients included in RelevarEM (NCT03375177).
Methods: The eligible study population and cohort selection included adult-onset patients (≥18 years) with definite MS. AMS were defined as those reaching confirmed EDSS ≥ 6 within 5 years from symptom onset.
Background: Myelin oligodendrocyte glycoprotein antibodies (MOG-ab) have been described in aquaporin-4-antibodies(AQP4-ab)-negative neuromyelitis optica spectrum disorder (NMOSD) patients. We aimed to evaluate the percentage of AQP4-ab-negative NMOSD patients who are positive for MOG-ab in a cohort of Argentinean patients included in RelevarEM (Clinical Trials registry number NCT03375177).
Methods: RelevarEM is a longitudinal, strictly observational multiple sclerosis (MS) and NMOSD registry in Argentina.