Publications by authors named "M Flamant"

Article Synopsis
  • The study focuses on SB5, an adalimumab biosimilar approved in Europe in 2017, and aims to gather real-world data on its usage and effectiveness in patients with various immune-mediated inflammatory diseases (IMIDs).
  • Researchers analyzed clinical and healthcare claims data from the French national healthcare database to assess patient persistence on SB5 after 12 months.
  • Among 911 patients treated with SB5, notable remission rates were observed at the 12-month mark, particularly in naïve patients, across various conditions such as rheumatoid arthritis and Crohn's disease, with all showing significant improvement from baseline.
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Article Synopsis
  • - The study investigates the effectiveness of Objective Structured Clinical Examinations (OSCEs) for evaluating medical students, revealing that while in-person assessments provide depth, they also lead to inconsistencies due to varying examiner standards.
  • - Data from 900 medical students at Université Paris Cité was analyzed over multiple OSCE sessions, showing significant differences in scores based on staff who graded them, highlighting the need for a statistical method to account for this variability.
  • - The results indicate that both staff and student variances affect OSCE scores, with staff variability being notably impactful; implementing two raters for consensus grading can help enhance score reliability.
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Background: The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker.

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