Publications by authors named "M Findik"
Article Synopsis
- Slow-release GnRH agonist implants are used in male dogs for contraception, and their effects are reversible, although safety concerns exist.
- A study was conducted to investigate the impact of these implants on testicular stress and androgen receptor signaling in dogs after the implants were removed, comparing them to untreated controls.
- Results showed both upregulation and downregulation of various proteins related to stress response and androgen receptors, indicating that GnRH implants do not increase cellular stress compared to natural breeding cycles, but more research is needed on hypoxic conditions.
Article Synopsis
- Nanotechnology has gained attention in biomedical applications over the last decade, particularly through the use of environmentally friendly green synthesis of metal and metal oxide nanoparticles (NPs), which are cost-effective and safe.
- The study focuses on synthesizing zinc oxide nanoparticles (ZnONPs) and metal-doped ZnONPs (with Mg and Ag) using plant extracts rich in phytochemicals, which serve as reducing and stabilizing agents.
- Characterization of the synthesized NPs revealed their size and shape through techniques like SEM and DLS, while also showing antibacterial activity against both Gram-positive and Gram-negative bacteria.
Correction: The use of a 4.7 mg deslorelin slow release implant in male dogs in the field.
Tierarztl Prax Ausg K Kleintiere Heimtiere
August 2023
The use of a 4.7 mg deslorelin slow release implant in male dogs in the field.
Tierarztl Prax Ausg K Kleintiere Heimtiere
August 2023
Objective: Slow-release GnRH agonist implants (SRI) are used for reversible medical downregulation of testicular function in male dogs as an alternative to surgery. The 4.7 mg deslorelin SRI should reduce testosterone after 6-8 weeks and induce castration-like effects for 6 months (mon).
View Article and Find Full Text PDFProgesterone (P4) is the only hormone needed to maintain pregnancy in dogs. Therefore, a competitive inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD) could be a safe and effective option to terminate pregnancy by inhibiting P4 synthesis. To address this hypothesis, we investigated the efficacy of trilostane (TRL), a competitive inhibitor of 3β-HSD, in terminating pregnancy in dogs.
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