Shearmetry of Fluids with Tunable Rheology by Polarized Luminescence of Rare Earth-Doped Nanorods.

Shear stress plays a critical role in regulating physiological processes within microcirculatory systems. While particle imaging velocimetry is a standard technique for quantifying shear flow, uncertainty near boundaries and low resolution remain severe restrictions. Additionally, shear stress determination is particularly challenging in biofluids due to their significant non-Newtonian behaviors.

Characterization of the ciliary beating efficiency in primary diffuse chronic rhinosinusitis.

Ciliary dysfunction may result in chronic airway inflammation and infection causing injury and structural changes to the airway epithelium, leading to a variety of diseases, like bronchiectasis and primary diffuse chronic rhinosinusitis (CRS). Currently, ciliary beating analysis has mainly been studied through the measure of the ciliary beating frequency (CBF) by high-speed digital video microscopy (HSDV). However, a normal CBF has been described in different forms of primary and acquired ciliary dyskinesia.

The Electronic Disorder Landscape of Mixed Halide Perovskites.

Band gap tunability of lead mixed halide perovskites makes them promising candidates for various applications in optoelectronics. Here we use the localization landscape theory to reveal that the static disorder due to iodide:bromide compositional alloying contributes at most 3 meV to the Urbach energy. Our modeling reveals that the reason for this small contribution is due to the small effective masses in perovskites, resulting in a natural length scale of around 20 nm for the "effective confining potential" for electrons and holes, with short-range potential fluctuations smoothed out.

Functional and structural consequences of epithelial cell invasion by Bordetella pertussis adenylate cyclase toxin.

Bordetella pertussis, the causative agent of whopping cough, produces an adenylate cyclase toxin (CyaA) that plays a key role in the host colonization by targeting innate immune cells which express CD11b/CD18, the cellular receptor of CyaA. CyaA is also able to invade non-phagocytic cells, via a unique entry pathway consisting in a direct translocation of its catalytic domain across the cytoplasmic membrane of the cells. Within the cells, CyaA is activated by calmodulin to produce high levels of cyclic adenosine monophosphate (cAMP) and alter cellular physiology.