Publications by authors named "M Figlerowicz"
Background: Group A Streptococci (GAS) may cause infections of the pharynx and soft tissues and invasive infections in children (iGAS). A significant increase in severe iGAS infections has been reported in Europe since the fall of 2022.
Objectives: This retrospective study aims to analyse clinical data of children with invasive and non-invasive GAS infections in the post-COVID-19 pandemic era, searching for predisposing factors to developing invasive infections.
Article Synopsis
- Lyme borreliosis (LB) is a significant health issue, causing numerous infections in children, and this study is the first to link it with environmental factors.
- Researchers analyzed medical records of 196 children diagnosed with LB in Poland and found a positive correlation between LB cases and environmental elements like deer density, broadleaved forest coverage, and urbanization.
- Results indicated that LB cases in children increased with urbanization and forest coverage, particularly in males, with a notable rise in cases from 2017 to 2021, highlighting the relationship between deer density and infection risk.
Treatment outcomes and their predictors in children hospitalized with varicella complicated by bacterial superinfections after pandemic of COVID-19 - a retrospective multicenter analysis of real-life data in Poland.
Eur J Clin Microbiol Infect Dis
December 2024
Article Synopsis
- The study aimed to evaluate treatment outcomes and predictors for children hospitalized with varicella complicated by bacterial infections, particularly after the COVID-19 pandemic.
- It analyzed data from 458 children, revealing that 69% fully recovered, while a small percentage experienced complications; GAS infection significantly raised the need for surgery.
- The findings indicated that using ibuprofen before treating varicella substantially increased the risk of complications and surgical interventions, while other pre-hospital treatments did not show significant effects.
This study investigates the impact of Epstein-Barr virus (EBV) infection on children's proteomes across different phases of the disease, utilising seventy-nine blood samples categorised into three groups: EBV-naive patients, acute infectious mononucleosis (IM) cases, and convalescents followed up for 12 months post-IM. The aim is to identify proteins influenced by EBV infection, shedding light on the chronic processes triggered by the virus. The results reveal thirty-nine proteins distinguishing between naive patients and those with IM, including actin, lumican, peroxiredoxin-2, fibulin-1, gelsolin, and alpha-2-macroglobulin, which are involved in immune responses, cell adhesion, and inflammation.
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