Publications by authors named "M Fevzi Celayir"
Following the results of the phase 3 KEYNOTE-522 trial, the U.S. Food and Drug Administration approved pembrolizumab, a humanized IgG4 kappa monoclonal antibody, in combination with neoadjuvant chemotherapy as a new standard of care for high-risk early-stage triple-negative breast cancer (TNBC).
View Article and Find Full Text PDFArticle Synopsis
- Meckel's diverticulum (MD) is the most common congenital gastrointestinal anomaly, found in about 2% of people, and is rarely symptomatic in adults.
- This case highlights a 46-year-old male who experienced abdominal pain due to Meckel's diverticulitis, which had formed a fistula with the abdominal wall, and was also found to have a benign inflammatory myofibroblastic tumor (IMT) on imaging.
- After surgery for the diverticulitis and complications like an anastomotic leak, the patient ultimately recovered, and this case emphasizes the importance of thorough diagnostic work to uncover incidental findings that can impact treatment.
Background: Colonoscopy difficulty and procedure time can vary between cases, posing challenges for daily scheduling in endoscopy units. In the literature, cecal intubation time (CIT) is commonly used to assess colonoscopy difficulty, yet there is debate regarding the factors influencing CIT. This prospective observational study aimed to evaluate the factors influencing CIT.
View Article and Find Full Text PDFIntroduction: The advances in immune checkpoint inhibitors (ICIs) were relatively slow in rare tumors. Therefore, we conducted a multi-center study evaluating the efficacy of ICI monotherapy and the combination of ICIs with chemotherapy (CT) in patients with advanced rare tumors.
Methods: In this retrospective cohort study, we included 93 patients treated with ICIs for NCI-defined rare tumors from the 12 cancer centers in Turkey.
Objective: We aimed to compare three endoscopy operators who performed colonoscopy in three different styles in terms of procedure results, colonoscopy quality, and operator comfort during the procedure.
Patients And Methods: A total of 246 patients, who underwent routine screening colonoscopy for precancerous lesions between May and December 2022 in Istanbul Haydarpaşa Numune Education and Research Hospital, Istanbul, Turkey, were prospectively analyzed. The results of three different styles ( , and ) were compared with each other.